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Fluvoxamine should not be used for the treatment of children and adolescents under 18 years except for patients with obsessive-compulsive disorder. Due to lack of clinical experience the use of fluvoxamine in children for the treatment of depression can not be recommended. In clinical studies conducted in children and adolescents due to suicidal-behavior (suicide attempts and thoughts), and hostility (mainly aggression, oppositional behavior and anger) were more frequent in patients treated with antidepressants compared to placebo. If, based on clinical need a decision to treat is accepted, the patient must be installed carefully monitored for appearance of suicidal symptoms.

In addition, long-term data on the safety of children and adolescents testosterone suspension for sale concerning growth, development and formation of cognitive behavior, no.

Adults (18 to 24 years old)
A meta-analysis of placebo-controlled clinical trials of antidepressants in adult patients with psychiatric disorders showed an increased risk of suicidal behavior with antidepressants compared to placebo in patients younger than 25 years. In the appointment of fluvoxamine should be related to the risk of suicide and the benefits of its application.

Elderly patients
Data from the treatment of elderly patients and younger patients showed no clinically relevant differences between them are usually used in daily doses. However, increasing doses of the drug in elderly patients should always be done slowly and with great care.

Akathisia / psychomotor agitation
development of akathisia associated with taking fluvoxamine, characterized subjectively unpleasant and painful anxiety. The need to move often accompanied by an inability to sit or stand still. The development of such a condition is most likely in the first few weeks of treatment. Increasing the dose of the drug in patients with such symptoms may worsen their condition.

Treatment of patients suffering from hepatic or renal insufficiency should start with low doses and such patients should be under strict medical supervision. In rare cases, treatment with fluvoxamine may increase the activity of hepatic enzymes, mostly accompanied by relevant clinical symptoms and in such cases, Luvox ® should be discontinued.

Nervous system disorders
Caution should be exercised when administering the drug to patients with seizures in history. Destination fluvoxamine should be avoided in patients with unstable epilepsy, and with stable epilepsy patients should be closely monitored. Treatment with testosterone suspension for sale should be discontinued if you experience seizures or their frequency increases.

Described rare cases of serotonin syndrome or condition, such neuroleptic malignant syndrome, which can be associated with taking fluvoxamine, especially in combination with other serotonergic and / or neuroleptic drugs. As these syndromes may result in potentially life-threatening condition, manifested by hyperthermia, muscle rigidity, myoclonus, lability of the autonomic nervous system with possible rapid changes in vital parameters (pulse, respiration, blood pressure, etc.), mental status changes, including confusion, irritability, extreme agitation that extends to delirium or coma – in such cases, treatment with fluvoxamine should be discontinued and should be initiated appropriate symptomatic treatment.

Disorders of metabolism and nutrition.
As with other selective serotonin reuptake inhibitors, in rare cases may cause hyponatremia, which is subjected to reverse development, after the abolition of fluvoxamine. Some cases have been caused by the syndrome of inadequate secretion of antidiuretic hormone. In general, these cases were observed in elderly patients.

It may be broken control of blood glucose levels (i.e., hyperglycemia, hypoglycemia, impaired glucose tolerance), especially in the early stages of treatment. In the case of the appointment of fluvoxamine in patients with diabetes mellitus history, you may need a dose adjustment of antidiabetic drugs.

The most frequently observed symptom associated , a nausea, sometimes accompanied by vomiting. This side effect is usually disappears within the first two weeks of treatment.

Hematologic abnormalities
have been reported such intradermal hemorrhages as ecchymosis and purpura and hemorrhagic manifestations (eg gastrointestinal bleeding) was observed with selective serotonin reuptake inhibitors. Caution must be exercised in the appointment of these drugs in elderly patients and in patients concomitantly receiving drugs acting on platelet function (eg, atypical antipsychotics and phenothiazines, most tricyclic antidepressants, aspirin, non-steroidal anti-inflammatory drugs) or drugs that increase the risk of bleeding, as well as in patients with a history of bleeding or prone to bleeding (eg, thrombocytopenia).

Disorders of cardiac activity
Increased risk of lengthening the interval testosterone suspension for sale ventricular tachycardia type “pirouette” in combination therapy with fluvoxamine terfenadine or astemizole, or cisapride, due to the increase of the concentration of the latter in the blood plasma. Therefore, fluvoxamine should not be administered with these drugs.

Fluvoxamine may cause a slight decrease in heart rate (2-6 beats per minute).

Reactions cancel
Upon termination of fluvoxamine may develop withdrawal symptoms, although the evidence of preclinical and clinical studies revealed no occurrence of the treatment with fluvoxamine. Symptoms noted in the case of cancellation of the product: dizziness, paresthesia, headache, nausea and anxiety. Most of these symptoms are poorly pronounced and stoped independently. A gradual reduction in dose is recommended for termination of drug treatment.

The ability to control the car and the use of machinery.
Luvox, are appointed to healthy volunteers in doses up to 150 mg did not influence or have a negligible effect on the ability to drive a car and operate the machine. At the same time there are reports of sleepiness notes during treatment with fluvoxamine. Therefore, caution is advised until the final testosterone suspension for sale determination of the individual response to the drug.